The Cancer Mechanobiology and Applied Biophysics group focuses on the investigation of tumor microenvironment mechanical and biophysical properties, the understanding of cancer and stromal cells mechanosensing and the cell-substrate interactions. Additionally, the study of tumor fibrosis, the role of collagen in cancer progression and the identification of collagen-based biomarkers lie within the group’s research interests. Although an important research goal is the identification of novel mechanical biomarkers for cancer diagnosis, prognosis and treatment monitoring, the group’s research interests also expand to other pathological conditions and unique biophysical research areas. The approaches used cover a wide spectrum of research techniques starting from assessment of cellular properties in vitro, experiments in whole animals, and finally validation in humans. Thus, cutting edge biophysical, bionengineering and biology techniques are employed, including advanced Atomic Force Microscopy techniques, which are among the research group’s expertise.